SCHEMBL9683454

SCHEMBL9683454

Nc1nc2c(c(=O)[nH]1)NCN2OCCCCP(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 10/20 0.61
PNP P00491 12/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9684323 0.96 HPRT1 (0.62) HPRT1PNP
SCHEMBL9857606 0.86 HPRT1 (0.69) HPRT1PNP
SCHEMBL9685499 0.84 HPRT1 (0.47) HPRT1PNP
SCHEMBL4242270 0.84 HPRT1 (0.50) HPRT1PNP
SCHEMBL9417162 0.84 HPRT1 (0.72) HPRT1PNP
SCHEMBL9683401 0.82 HPRT1 (0.56) HPRT1PNP
SCHEMBL9683728 0.81 HPRT1 (0.47) HPRT1PNP
SCHEMBL9684438 0.80 HPRT1 (0.54) HPRT1PNP
SCHEMBL9576807 0.80 HPRT1 (0.67) HPRT1PNP
SCHEMBL9515983 0.80 HPRT1 (0.72) HPRT1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0404296-A1 Phosphono derivatives of purine with antiviral activity Beecham Group p.l.c. (GB) 1990-12-27 EP claimed
US-5166198-A Herpes virus infections BEECHAM P.L.C. (GB) 1992-11-24 US disclosed
EP-0404296-A1 Phosphono derivatives of purine with antiviral activity Beecham Group p.l.c. (GB) 1990-12-27 EP disclosed