Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394893 | 0.85 | TP53 (0.50) | TDP1ALDH1A1KMT2AF2PLAU | |
| SCHEMBL9831007 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2APOLBSMN1; SMN2NR3C2 | |
| SCHEMBL3165138 | 0.76 | ALDH1A1 (0.46) | TDP1ALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL23023963 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2ASMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL30529302 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2ASMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL7234625 | 0.75 | NR3C2 (0.45) | ALDH1A1KMT2AF2PLAUKLKB1 | |
| SCHEMBL14711327 | 0.73 | SLC5A1 (0.48) | ALDH1A1KMT2APOLBSMN1; SMN2RAB9A | |
| SCHEMBL13624226 | 0.73 | PDE4D (0.58) | ALDH1A1KMT2APOLBSMN1; SMN2RAB9A | |
| SCHEMBL2358435 | 0.73 | KMT2A (0.58) | ALDH1A1KMT2AGAARAB9ANPC1 | |
| SCHEMBL1013106 | 0.72 | CYP2C9 (0.54) | ALDH1A1SMN1; SMN2NR3C2RAB9ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082949-A | Plant growth regulators, protective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |