Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575271 | 0.83 | NR3C2 (0.46) | ALDH1A1KMT2ANR3C2KDM5AKDM2B | |
| SCHEMBL9683620 | 0.76 | TDP1 (0.46) | ALDH1A1KMT2ANR3C2RAB9ASMN1; SMN2 | |
| SCHEMBL9833146 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL18256262 | 0.72 | NPBWR1 (0.45) | ALDH1A1KMT2AKDM5AKDM2BKDM4C | |
| SCHEMBL1013106 | 0.71 | CYP2C9 (0.54) | ALDH1A1NR3C2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18256245 | 0.70 | KDM5A (0.49) | ALDH1A1KMT2AKDM5AKDM2BKDM4C | |
| SCHEMBL3417583 | 0.69 | POLB (0.50) | KMT2ANR3C2KDM5AKDM4CKDM5B | |
| SCHEMBL26983243 | 0.69 | POLB (0.46) | ALDH1A1RAB9ASMN1; SMN2NPC1NPSR1 | |
| SCHEMBL23401516 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KMT2ANR3C2RAB9ASMN1; SMN2 | |
| SCHEMBL1598492 | 0.68 | LMNA (0.61) | ALDH1A1KMT2ARAB9ANPC1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269806-B1 | PHENYLPYRAZOLE CARBONIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS PLANT GROWTH REGULATORS AND ANTIDOTES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0269806-A1 | Phenylpyrazole carbonic acid derivatives, their preparation and use as plant growth regulators and antidotes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-08 | — | — | EP | disclosed |