SCHEMBL9683698

SCHEMBL9683698

CCOP(=O)(CC(CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)OCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10439391 0.85 TSHR (0.43) TSHR
SCHEMBL9858000 0.84 TSHR (0.31) TSHR
SCHEMBL9684165 0.83 PPARD (0.38) TSHRPPARD
SCHEMBL9655920 0.81 TSHR (0.32) TSHR
SCHEMBL13847578 0.79 MAPT (0.35) TSHRPPARD
SCHEMBL26726102 0.76
SCHEMBL9858037 0.74 TSHR (0.30) TSHR
SCHEMBL9858325 0.72 PPARD (0.34) TSHRPPARD
SCHEMBL9684317 0.72 PPARD (0.40) TSHRPPARD
SCHEMBL9683768 0.72 PPARD (0.43) TSHRPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166198-A Herpes virus infections BEECHAM P.L.C. (GB) 1992-11-24 US disclosed
EP-0404296-A1 Phosphono derivatives of purine with antiviral activity Beecham Group p.l.c. (GB) 1990-12-27 EP disclosed