Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684165 | 0.82 | PPARD (0.38) | TSHR | |
| SCHEMBL9683698 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL13847578 | 0.78 | MAPT (0.35) | TSHR | |
| SCHEMBL9655927 | 0.74 | — | — | |
| SCHEMBL27620257 | 0.74 | CA2 (0.30) | — | |
| SCHEMBL9683768 | 0.73 | PPARD (0.43) | TSHR | |
| SCHEMBL16325223 | 0.73 | — | — | |
| SCHEMBL10439391 | 0.70 | TSHR (0.43) | TSHR | |
| SCHEMBL9858000 | 0.69 | TSHR (0.31) | TSHR | |
| SCHEMBL14459806 | 0.69 | PPARD (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479640-A2 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| EP-0477454-A1 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-01 | — | — | EP | disclosed |