SCHEMBL9684165

SCHEMBL9684165

CCOP(=O)(CC(CO)O[Si](C)(C)C(C)(C)C)OCC

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.38
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683768 0.85 PPARD (0.43) PPARDTSHR
SCHEMBL13847578 0.84 MAPT (0.35) PPARDTSHRMAPTMAPK1
SCHEMBL9683698 0.83 TSHR (0.33) PPARDTSHR
SCHEMBL9858325 0.82 PPARD (0.34) PPARDTSHR
SCHEMBL9655920 0.82 TSHR (0.32) TSHR
SCHEMBL9858024 0.76 TSHR (0.35) TSHR
SCHEMBL5806133 0.75 PRKCA (0.32)
SCHEMBL15524499 0.74
SCHEMBL15524497 0.74
SCHEMBL4570492 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166198-A Herpes virus infections BEECHAM P.L.C. (GB) 1992-11-24 US disclosed
EP-0404296-A1 Phosphono derivatives of purine with antiviral activity Beecham Group p.l.c. (GB) 1990-12-27 EP disclosed