Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393915 | 0.85 | KDM4E (0.69) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL118687 | 0.85 | KDM4E (0.78) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL12266541 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL9368699 | 0.84 | KDM4E (0.68) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL4203942 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL4892442 | 0.83 | KDM4E (0.66) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL5454067 | 0.82 | KDM4E (0.73) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL9472025 | 0.82 | KDM4E (0.73) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL2583451 | 0.82 | KDM4E (0.73) | ALDH1A1KDM4ECREBBPENPP2GRIN2D | |
| SCHEMBL172191 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4ECREBBPENPP2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |