SCHEMBL9683758

SCHEMBL9683758

COc1cc(OC)nc(Oc2cccc(Cl)c2C(=O)NS(=O)(=O)C(C)C)n1

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CTSA P10619 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683769 0.82 ALDH1A1 (0.56) NPSR1ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL9045943 0.81 NPSR1 (0.62) NPSR1ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL8939116 0.79 NPSR1 (0.60) NPSR1ALDH1A1SMN1; SMN2
Isopropylamine SCHEMBL9871415 0.79 NPSR1 (0.58) NPSR1CYP1A2CYP2C9CYP2C19ATM
SCHEMBL9873475 0.78 NPSR1 (0.59) NPSR1ALDH1A1SMN1; SMN2
SCHEMBL9681963 0.78 SCN9A (0.45) NPSR1
SCHEMBL9622844 0.77 NPSR1 (0.58) NPSR1ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL9622225 0.77 NPSR1 (0.58) NPSR1ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL8939153 0.76 NPSR1 (0.60) NPSR1ALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL9622238 0.76 NPSR1 (0.55) NPSR1ALDH1A1SMN1; SMN2CTSACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5149357-A Herbicidal substituted benzoylsulfonamides FMC CORPORATION (US) 1992-09-22 US disclosed