Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272803 | 0.90 | MTNR1B (0.50) | BLMTSHR | |
| SCHEMBL14356155 | 0.90 | MTNR1B (0.50) | BLMTSHR | |
| SCHEMBL30301824 | 0.85 | FFAR1 (0.52) | BLMTSHRHTTALDH1A1XBP1 | |
| SCHEMBL3590904 | 0.85 | FFAR1 (0.52) | BLMTSHRHTTALDH1A1XBP1 | |
| SCHEMBL1568052 | 0.85 | BLM (0.51) | BLMTSHRHTTALDH1A1XBP1 | |
| SCHEMBL30572310 | 0.84 | BLM (0.50) | BLMTSHRHTTALDH1A1XBP1 | |
| SCHEMBL10584761 | 0.84 | TSHR (0.50) | BLMTSHRHTTALDH1A1XBP1 | |
| SCHEMBL1725811 | 0.84 | BLM (0.50) | BLMTSHRHTTALDH1A1XBP1 | |
| SCHEMBL5951346 | 0.83 | TSHR (0.47) | BLMTSHRHTTALDH1A1XBP1 | |
| SCHEMBL7038866 | 0.83 | HAO1 (0.53) | BLMTSHRHTTALDH1A1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0404197-A2 | Arylalkylamine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |