SCHEMBL9683837

SCHEMBL9683837

CCc1cc(CC)c(Br)c(CC)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
PTPN1 P18031 4/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HSPA5 P11021 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ATP1A1 P05023 1/20 0.32
ATP1B1 P05026 1/20 0.32
ATP1A3 P13637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29104177 0.83 KDM4E (0.37) GABRA1GABRB2PTPN1CA1CA2
SCHEMBL25328782 0.79 GABRA1 (0.42) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL31092542 0.79 GABRA1 (0.42) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL4920699 0.79 KDM4E (0.33) KDM4EGLAGAA
SCHEMBL31092541 0.77 GABRA1 (0.41) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL25327893 0.77 GABRA1 (0.41) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL29126153 0.77 GABRA1 (0.37) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL11209888 0.75 GABRA1 (0.42) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL8371103 0.74 GABRA1 (0.46) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL1760472 0.73 ALOX15 (0.43) GABRA1GABRB2PTPN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098963-A Cresol-formaldehyde resin and 3,5-dibromo-2,4,6-trimethyl phenol for encapsulation of electronics THE DOW CHEMICAL COMPANY (US) 1992-03-24 US claimed
US-5028668-A Encapsulation of Electronics THE DOW CHEMICAL COMPANY (US) 1991-07-02 US claimed
US-4975500-A Encapsulation electronics THE DOW CHEMICAL COMPANY (US) 1990-12-04 US claimed
US-4914185-A FOR ENCAPSULATING ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-04-03 US claimed
EP-0242697-A2 Adducts of metabrominated phenols and polyfunctional epoxides THE DOW CHEMICAL COMPANY (US) 1987-10-28 EP claimed
US-5098963-A Cresol-formaldehyde resin and 3,5-dibromo-2,4,6-trimethyl phenol for encapsulation of electronics THE DOW CHEMICAL COMPANY (US) 1992-03-24 US disclosed
US-5028668-A Encapsulation of Electronics THE DOW CHEMICAL COMPANY (US) 1991-07-02 US disclosed
US-4975500-A Encapsulation electronics THE DOW CHEMICAL COMPANY (US) 1990-12-04 US disclosed
US-4914185-A FOR ENCAPSULATING ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-04-03 US disclosed
EP-0242697-A2 Adducts of metabrominated phenols and polyfunctional epoxides THE DOW CHEMICAL COMPANY (US) 1987-10-28 EP disclosed