Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682499 | 0.83 | PBRM1 (0.51) | — | |
| SCHEMBL9681993 | 0.80 | SCN9A (0.39) | SCN9A | |
| SCHEMBL9683066 | 0.75 | DHODH (0.41) | MAPTPTK2TP53GLAGAA | |
| SCHEMBL9683663 | 0.72 | MAPT (0.42) | MAPTGAACYP1A2 | |
| SCHEMBL9681963 | 0.71 | SCN9A (0.45) | SCN9A | |
| SCHEMBL21280661 | 0.70 | TP53 (0.50) | MAPTTP53CYP1A2 | |
| SCHEMBL8111084 | 0.70 | CDK1 (0.47) | MAPTMAPK1TP53GLAGAA | |
| SCHEMBL10949384 | 0.69 | GAA (0.52) | MAPTMAPK1TP53GLAGAA | |
| SCHEMBL8069688 | 0.69 | CCR4 (0.44) | MAPTTP53GLAGAA | |
| SCHEMBL9683758 | 0.68 | NPSR1 (0.50) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149357-A | Herbicidal substituted benzoylsulfonamides | FMC CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |