SCHEMBL5954786

SCHEMBL5954786

C=CCOc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.34
HTR2C P28335 6/20 0.33
HTR2B P41595 4/20 0.33
HTR2A P28223 4/20 0.32
ADRB2 P07550 2/20 0.32
HTR1A P08908 2/20 0.32
CHRM5 P08912 2/20 0.32
ADRA2A P08913 2/20 0.32
DRD2 P14416 2/20 0.32
ADRA2B P18089 2/20 0.32
ADRA2C P18825 2/20 0.32
DRD4 P21917 2/20 0.32
HRH2 P25021 2/20 0.32
SLC6A4 P31645 2/20 0.32
HTR7 P34969 2/20 0.32
DRD3 P35462 2/20 0.32
HTR6 P50406 2/20 0.32
KCNH2 Q12809 2/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14585700 0.93 TLR4 (0.32) TLR4HTR2CHTR2B
SCHEMBL22722397 0.86 CA12 (0.32) TLR4CA12CA1CA2CA7
SCHEMBL19871282 0.84 HTR2C (0.32) TLR4HTR2CHTR2BHTR2ACA12
SCHEMBL16448289 0.84 TLR4 (0.30) TLR4
SCHEMBL10995320 0.83 TLR4 (0.33) TLR4
SCHEMBL18210491 0.81 HTR2C (0.41) TLR4HTR2CHTR2BHTR2AADRB2
SCHEMBL4316306 0.81 MAPT (0.34) TLR4MAPTMAPK1
SCHEMBL10336944 0.81 MGAM (0.33) TLR4
SCHEMBL10826508 0.74 SQOR (0.34)
SCHEMBL26489534 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119695269-A Solid polymer electrolyte membrane, method for producing the same, solid battery, and mechanical device 重庆太蓝新能源有限公司 2025-03-25 CN claimed
CN-116315080-A Low-temperature electrolyte, lithium-sulfur battery and preparation method of lithium-sulfur battery 蜂巢能源科技(无锡)有限公司 2023-06-23 CN claimed
CN-119695269-A Solid polymer electrolyte membrane, method for producing the same, solid battery, and mechanical device 重庆太蓝新能源有限公司 2025-03-25 CN disclosed
CN-116315080-A Low-temperature electrolyte, lithium-sulfur battery and preparation method of lithium-sulfur battery 蜂巢能源科技(无锡)有限公司 2023-06-23 CN disclosed
CN-115466284-A Halogenated phosphite ester containing branched chain, preparation method and application thereof 恒大新能源技术(深圳)有限公司 2022-12-13 CN disclosed
CN-115448947-A Halogenated phosphate containing branched chain, preparation method and application thereof 恒大新能源技术(深圳)有限公司 2022-12-09 CN disclosed
CN-115084655-A Electrolyte, preparation method thereof and lithium metal battery containing electrolyte 蜂巢能源科技(无锡)有限公司 2022-09-20 CN disclosed
CN-112625245-B Chloro/epoxy group fluorine-containing silicone oil and application thereof in room temperature vulcanized fluorosilicone rubber 东莞市雄驰电子有限公司 2022-07-12 CN disclosed
CN-112625245-A Chloro/epoxy group fluorine-containing silicone oil and application thereof in room temperature vulcanized fluorosilicone rubber 东莞市雄驰电子有限公司 2021-04-09 CN disclosed
WO-2018127654-A1 FUNCTIONALISED CELLULOSE MATERIAL UNIVERSITE DE NANTES (FR) 2018-07-12 WO disclosed
US-20180042843-A1 HIGH DENSITY PEPTIDE POLYMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-02-15 US disclosed
US-20170327633-A1 COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-11-16 US disclosed
US-7115706-B2 Polyether polymers and compositions derived therefrom BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2006-10-03 US disclosed
US-20050209430-A1 Polyether polymers and compositions derived therefrom BOARD OF TRUSTEES MICHIGAN STATE UNIVERSITY (US) 2005-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180042843-A1 HIGH DENSITY PEPTIDE POLYMERS ERMP1, PARL, PRAP1 TLR4 1717/4885HTR2C 3334/4885HTR2B 2081/4885
US-20170327633-A1 COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS RNGTT, NSUN2, POLN TLR4 3390/4885HTR2C 4558/4885HTR2B 4410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.