Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976204 | 1.00 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL28364860 | 1.00 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL28369056 | 1.00 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL17093303 | 1.00 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL60356 | 0.83 | AOC3 (0.57) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL9683893 | 0.83 | AOC3 (0.57) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL28364979 | 0.82 | MEN1 (0.44) | LMNACYP2D6KDM4EALDH1A1KMT2A | |
| SCHEMBL29008441 | 0.81 | CYP2D6 (0.43) | LMNACES2CES1MAPK1L3MBTL1 | |
| SCHEMBL16654109 | 0.79 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 | |
| SCHEMBL5860193 | 0.79 | AOC3 (0.48) | AOC3LMNACES2CES1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11896593-B2 | Sulfamate derivative compounds for use in treating or alleviating a psychiatric disorder | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2024-02-13 | — | — | US | disclosed |
| US-9221783-B2 | Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-12-29 | — | — | US | disclosed |
| US-20150266848-A1 | PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-09-24 | — | — | US | disclosed |
| US-6780810-B2 | HYDROXYLATION CATALYST COMPRISING A CATALYST SUPPORT WITH TWO OR MORE ACTIVE TRANSITION METALS, FOR THE REACTION OF STYRENE AND IODOBENZENE TO FORM 1,2-DIPHENYL-1,2-ETHANEDIOL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-08-24 | — | — | US | disclosed |
| EP-1346767-A1 | Multifunctional catalyst useful in the synthesis of chiral vicinal diols and process for the preparation thereof | Council of Scientific and Industrial Research (IN) | 2003-09-24 | — | — | EP | disclosed |
| US-20030176746-A1 | Multifunctional catalyst useful in the synthesis of chiral vicinal diols and process for the preparation thereof, and process for the preparation of chiral vicinal diols using said multifunctional catalysts | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-09-18 | — | — | US | disclosed |
| EP-0643781-B1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR INC (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5419817-A | Osmium tetroxide catalyst; preparing hydroxycarbonyl compounds from enol ether or vinyl halide | SEPRACOR INC. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0643781-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5302257-A | Preparing optically active glycols using catalyst complex of osmium tetroxide and chiral oxidation resistant tertiary amine, employing secondary oxidant to generate osmium tetroxide, electrolytically regenerating secondary oxidant | SEPRACOR, INC. (US) | 1994-04-12 | — | — | US | disclosed |
| WO-1993017150-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1993-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266848-A1 | PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME | MYLK, MUSK, MYLK2 | AOC3 3744/4885LMNA 1666/4885CES2 2189/4885 |
| US-11896593-B2 | Sulfamate derivative compounds for use in treating or alleviating a psychiatric disorder | SLC6A4, SLC6A3, SLC6A2 | AOC3 2665/4885LMNA 4792/4885CES2 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.