Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1020434 | 0.92 | OPRM1 (0.70) | OPRM1 | |
| SCHEMBL23512881 | 0.86 | OPRM1 (0.64) | OPRM1CYP1A2 | |
| SCHEMBL2441730 | 0.84 | OPRM1 (0.66) | OPRM1POLB | |
| SCHEMBL625524 | 0.84 | OPRM1 (0.66) | OPRM1POLB | |
| SCHEMBL17761267 | 0.83 | OPRM1 (0.44) | OPRM1CYP1A2CYP2D6 | |
| SCHEMBL181275 | 0.82 | OPRM1 (0.64) | OPRM1POLB | |
| SCHEMBL10000801 | 0.81 | OPRM1 (0.58) | OPRM1CYP2D6 | |
| SCHEMBL13594179 | 0.79 | OPRM1 (0.60) | OPRM1 | |
| SCHEMBL11093941 | 0.78 | OPRM1 (0.58) | OPRM1 | |
| SCHEMBL21376918 | 0.76 | OPRM1 (0.53) | OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485929-A1 | Substituted azoles, process for their preparation and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-20 | — | — | EP | disclosed |