Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376918 | 0.90 | OPRM1 (0.53) | OPRM1CCR2CYP2D6 | |
| SCHEMBL1020434 | 0.85 | OPRM1 (0.70) | OPRM1 | |
| SCHEMBL22241035 | 0.84 | HSD11B1 (0.45) | OPRM1CYP2D6 | |
| SCHEMBL17761262 | 0.84 | CYP2D6 (0.49) | OPRM1CCR2CYP2D6 | |
| SCHEMBL16591279 | 0.84 | CYP2D6 (0.49) | OPRM1CCR2CYP2D6 | |
| SCHEMBL13450003 | 0.84 | OPRM1 (0.49) | OPRM1CYP2D6 | |
| SCHEMBL9683897 | 0.81 | OPRM1 (0.62) | OPRM1CYP2D6 | |
| SCHEMBL625524 | 0.81 | OPRM1 (0.66) | OPRM1 | |
| SCHEMBL2441730 | 0.81 | OPRM1 (0.66) | OPRM1 | |
| SCHEMBL17146951 | 0.81 | OPRM1 (0.38) | OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |