Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | CDC25A | P30304 | 3/20 | 0.35 |
| ▸ | CDC25B | P30305 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683936 | 1.00 | PTPRC (0.41) | PTPRCMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9685859 | 0.81 | MAPT (0.36) | PTPRCMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9685863 | 0.81 | MAPT (0.36) | PTPRCMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9685509 | 0.77 | PTPRC (0.50) | PTPRCMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9270325 | 0.70 | PTPRC (0.57) | PTPRCMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9684473 | 0.69 | MAPT (0.54) | PTPRCMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL11077569 | 0.67 | MCL1 (0.58) | PTPRCMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8954279 | 0.65 | PTPRC (0.50) | PTPRCMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL14266378 | 0.65 | KMT2A (0.44) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL5110610 | 0.65 | KMT2A (0.44) | MAPTALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |