Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | S100A4 | P26447 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302518 | 0.79 | CDC25B (0.47) | PTPRCMEN1KMT2AMAPTS100A4 | |
| SCHEMBL9270325 | 0.78 | PTPRC (0.57) | PTPRCMEN1KMT2AMAPTMAOA | |
| SCHEMBL16272402 | 0.77 | ERN1 (0.45) | PTPRCS100A4CES1ALDH1A1ERN1 | |
| SCHEMBL9683936 | 0.77 | PTPRC (0.41) | PTPRCMEN1KMT2AMAPTMAOA | |
| SCHEMBL9683931 | 0.77 | PTPRC (0.41) | PTPRCMEN1KMT2AMAPTMAOA | |
| SCHEMBL5158317 | 0.76 | MAPT (0.48) | PTPRCMEN1KMT2AMAPTMAOA | |
| SCHEMBL9684783 | 0.76 | MAPT (0.37) | PTPRCMEN1KMT2AMAPTMAOA | |
| SCHEMBL11077569 | 0.75 | MCL1 (0.58) | PTPRCMEN1KMT2AMAPTMAOA | |
| SCHEMBL7462537 | 0.74 | PTPRC (0.55) | PTPRCMEN1KMT2AMAPTPOLB | |
| SCHEMBL8954279 | 0.72 | PTPRC (0.50) | PTPRCMEN1KMT2AMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |