Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 7/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.33 |
| ▸ | CDC25A | P30304 | 3/20 | 0.33 |
| ▸ | CDC25B | P30305 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685859 | 1.00 | MAPT (0.36) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9683931 | 0.81 | PTPRC (0.41) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9683936 | 0.81 | PTPRC (0.41) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9684783 | 0.80 | MAPT (0.37) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9684465 | 0.70 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9684457 | 0.69 | SRC (0.41) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9684460 | 0.69 | SRC (0.41) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9684529 | 0.69 | ALDH1A1 (0.40) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9423239 | 0.69 | MAPT (0.38) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL9685886 | 0.69 | CDC25B (0.42) | MAPTALDH1A1KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |