Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.31 |
| ▸ | WNT3A | P56704 | 5/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759805 | 0.92 | ALDH1A1 (0.32) | ALDH1A1CTNNB1WNT3AMAPT | |
| SCHEMBL8785080 | 0.88 | ALDH1A1 (0.33) | ALDH1A1KDM4EHTR1AHTR2ADRD3 | |
| SCHEMBL9483714 | 0.88 | ALDH1A1 (0.33) | ALDH1A1KDM4EHTR1AHTR2ADRD3 | |
| SCHEMBL9484633 | 0.87 | HSD17B3 (0.44) | HTR7HRH1 | |
| SCHEMBL9483505 | 0.84 | PKM (0.43) | ALDH1A1RAB9ACTNNB1WNT3A | |
| SCHEMBL9484797 | 0.84 | HPGD (0.43) | ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL9483054 | 0.81 | ATM (0.41) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL8786917 | 0.81 | PTPN1 (0.41) | — | |
| SCHEMBL5727378 | 0.76 | MAPT (0.39) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9483366 | 0.74 | SRD5A2 (0.41) | ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |