Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287067 | 0.80 | TDP1 (0.34) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL9657795 | 0.79 | TP53 (0.37) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL10549828 | 0.78 | USP2 (0.33) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL11277515 | 0.78 | USP2 (0.35) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL232171 | 0.78 | TP53 (0.57) | TP53CYP3A4ALDH1A1 | |
| SCHEMBL29753313 | 0.77 | MAPK1 (0.37) | TP53CYP3A4ALDH1A1TDP1MAPT | |
| Water SCHEMBL18428586 | 0.77 | TP53 (0.55) | TP53CYP3A4ALDH1A1 | |
| SCHEMBL1143090 | 0.76 | ALDH1A1 (0.47) | USP2ALDH1A1ALOX15TDP1MAPT | |
| SCHEMBL10349616 | 0.75 | TP53 (0.33) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL9717816 | 0.75 | MAPT (0.33) | USP2ALDH1A1ALOX15TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481476-A2 | Trifunctional unsaturated compounds and derivatives thereof | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-04-22 | — | — | EP | disclosed |