Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277515 | 0.81 | USP2 (0.35) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL11287067 | 0.80 | TDP1 (0.34) | TP53CYP3A4LMNAUSP2ALDH1A1 | |
| SCHEMBL9684043 | 0.79 | TP53 (0.34) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL10549828 | 0.78 | USP2 (0.33) | TP53CYP3A4USP2ALDH1A1ALOX15 | |
| SCHEMBL11277849 | 0.76 | HPGD (0.42) | ALDH1A1TDP1 | |
| SCHEMBL15128324 | 0.74 | ALDH1A1 (0.38) | CYP3A4CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL11282473 | 0.74 | USP2 (0.35) | LMNAUSP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL11289199 | 0.73 | USP2 (0.31) | USP2ALDH1A1ALOX15TDP1 | |
| SCHEMBL28413233 | 0.73 | USP2 (0.36) | TP53CYP3A4CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL28413234 | 0.71 | USP2 (0.35) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479166-A1 | Transesterification process for preparation of cycloaliphatic epoxides | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-04-08 | — | — | EP | disclosed |