Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582021 | 0.74 | HPGD (0.47) | HPGDPARP1ALDH1A1PDPK1PIM1 | |
| SCHEMBL22139858 | 0.72 | HPGD (0.44) | HPGDPARP1ALDH1A1PDPK1PIM1 | |
| SCHEMBL9723069 | 0.71 | HPGD (0.44) | HPGDPARP1ALDH1A1PDPK1PIM1 | |
| SCHEMBL9723056 | 0.71 | HPGD (0.41) | HPGDPARP1ALKALDH1A1PDPK1 | |
| SCHEMBL9340305 | 0.71 | HPGD (0.43) | HPGDPARP1ALDH1A1PDPK1PIM1 | |
| SCHEMBL4231028 | 0.71 | HPGD (0.67) | HPGDPARP1ALDH1A1PDPK1PIM1 | |
| SCHEMBL9723032 | 0.71 | HPGD (0.47) | HPGDPARP1ALDH1A1PDPK1PIM1 | |
| SCHEMBL9723036 | 0.70 | HPGD (0.40) | HPGDPARP1ALDH1A1PIM1PIM3 | |
| SCHEMBL9723132 | 0.68 | HPGD (0.41) | HPGDPARP1ALKALDH1A1PDPK1 | |
| SCHEMBL9683218 | 0.68 | HPGD (0.38) | HPGDPARP1ALDH1A1KDM5BPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481604-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-22 | — | — | EP | disclosed |