Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 12/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684241 | 1.00 | ADRB1 (0.65) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL8757430 | 0.94 | ADRB3 (0.63) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL8757427 | 0.94 | ADRB3 (0.63) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL8757490 | 0.91 | ADRB3 (0.57) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL8757495 | 0.91 | ADRB3 (0.57) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL10365832 | 0.91 | ADRB2 (0.60) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL8758298 | 0.90 | ADRB3 (0.64) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL8758301 | 0.90 | ADRB3 (0.64) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL8758191 | 0.89 | ADRB3 (0.56) | ADRB1ADRB3ADRB2GLAMEN1 | |
| SCHEMBL8758187 | 0.89 | ADRB3 (0.56) | ADRB1ADRB3ADRB2GLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |