Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845408 | 0.82 | POLB (0.50) | POLB | |
| SCHEMBL9684130 | 0.82 | POLB (0.50) | POLBHTTATMCYP2C19 | |
| SCHEMBL26858087 | 0.78 | CYP1A2 (0.46) | POLBHTTCYP2C19 | |
| SCHEMBL9684264 | 0.77 | POLB (0.61) | POLB | |
| SCHEMBL5161230 | 0.77 | HTT (0.38) | POLBHTT | |
| SCHEMBL9683683 | 0.77 | POLB (0.61) | POLBHTTCYP2C19 | |
| SCHEMBL15002989 | 0.76 | TAAR1 (0.37) | — | |
| SCHEMBL21546205 | 0.76 | FABP4 (0.46) | POLBHTT | |
| SCHEMBL20706615 | 0.76 | HTT (0.37) | POLBHTT | |
| SCHEMBL15957594 | 0.76 | POLB (0.43) | POLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492473-A1 | Process for the preparation of 4-substituted 2,6-dialkylanilines | LONZA AG (CH) | 1992-07-01 | — | — | EP | disclosed |