Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682612 | 0.90 | CYP2D6 (0.52) | CYP2D6MC4RCCR5LMNASMN1; SMN2 | |
| SCHEMBL9683895 | 0.83 | CYP2D6 (0.55) | CYP2D6MC4RCCR5LMNASMN1; SMN2 | |
| SCHEMBL5283241 | 0.83 | DPP4 (0.41) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9682542 | 0.80 | CYP2D6 (0.47) | CYP2D6MC4RCCR5LMNASMN1; SMN2 | |
| SCHEMBL14139752 | 0.77 | KMT2A (0.58) | ALDH1A1KMT2A | |
| SCHEMBL9681972 | 0.77 | CYP2D6 (0.47) | CYP2D6MC4RCCR5LMNASMN1; SMN2 | |
| SCHEMBL18610248 | 0.76 | CYP2D6 (0.46) | CYP2D6MC4RCCR5LMNASMN1; SMN2 | |
| SCHEMBL18610054 | 0.76 | MC4R (0.57) | CYP2D6MC4RCCR5LMNASMN1; SMN2 | |
| SCHEMBL9682087 | 0.76 | OPRL1 (0.44) | CYP2D6MC4ROPRL1ALDH1A1MAPT | |
| SCHEMBL7459001 | 0.75 | LMNA (0.55) | CYP2D6MC4RCCR5LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |