Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683068 | 0.86 | KMT2A (0.46) | OPRL1CYP2D6MAPTALDH1A1 | |
| SCHEMBL9682542 | 0.86 | CYP2D6 (0.47) | OPRL1CYP2D6MAPTALDH1A1MC4R | |
| SCHEMBL844722 | 0.79 | LMNA (0.51) | OPRL1CYP2D6MAPTALDH1A1CHRM4 | |
| SCHEMBL6631278 | 0.79 | LMNA (0.51) | OPRL1CYP2D6MAPTALDH1A1CHRM4 | |
| SCHEMBL19914765 | 0.78 | OPRL1 (0.41) | OPRL1CYP2D6MAPTALDH1A1MC4R | |
| SCHEMBL9682612 | 0.78 | CYP2D6 (0.52) | OPRL1CYP2D6MAPTALDH1A1MC4R | |
| SCHEMBL9684280 | 0.76 | CYP2D6 (0.49) | OPRL1CYP2D6MAPTALDH1A1MC4R | |
| SCHEMBL9682596 | 0.76 | CYP2D6 (0.49) | CYP2D6MAPTALDH1A1MC4R | |
| SCHEMBL9683895 | 0.75 | CYP2D6 (0.55) | OPRL1CYP2D6MAPTALDH1A1MC4R | |
| SCHEMBL18610146 | 0.74 | NAMPT (0.49) | MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |