Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 9/20 | 0.45 |
| ▸ | PNP | P00491 | 7/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858167 | 0.86 | FGFR1 (0.49) | HPRT1PNPNT5ECDK1CCNB1 | |
| SCHEMBL9684116 | 0.84 | FGFR1 (0.52) | HPRT1PNPFGFR1SLC22A6 | |
| SCHEMBL9684374 | 0.84 | CDK1 (0.43) | HPRT1PNPNT5ECDK1CCNB1 | |
| SCHEMBL9417176 | 0.83 | FGFR1 (0.51) | HPRT1PNPNT5ECDK1CCNB1 | |
| SCHEMBL9683440 | 0.80 | PNP (0.70) | HPRT1PNP | |
| SCHEMBL9685282 | 0.80 | FGFR1 (0.53) | HPRT1FGFR1SLC22A6 | |
| SCHEMBL9685345 | 0.78 | CDK1 (0.40) | HPRT1NT5ECDK1CCNB1CCNE1 | |
| SCHEMBL29003399 | 0.77 | HPRT1 (0.59) | HPRT1PNPCDK1CCNB1CCNE1 | |
| SCHEMBL9684292 | 0.76 | HPRT1 (0.69) | HPRT1PNP | |
| SCHEMBL9858125 | 0.75 | CDK1 (0.41) | PNPNT5ECDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | claimed |
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |