Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | FBP1 | P09467 | 2/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684116 | 0.96 | FGFR1 (0.52) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL9857536 | 0.86 | FGFR1 (0.65) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL6334793 | 0.84 | FGFR1 (0.61) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL29391225 | 0.84 | FGFR1 (0.68) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL2107417 | 0.84 | FGFR1 (0.68) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL9683747 | 0.83 | ADORA2A (0.43) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL9677373 | 0.81 | FGFR1 (0.50) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL9685561 | 0.81 | CYP3A4 (0.47) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A | |
| SCHEMBL9684339 | 0.80 | HPRT1 (0.45) | FGFR1SLC22A6HPRT1 | |
| SCHEMBL9683437 | 0.80 | CYP3A4 (0.43) | FGFR1SLC22A6ENPP1CYP3A4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | claimed |
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |