Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 1.00 |
| ▸ | METAP2 | P50579 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420370 | 1.00 | REN (1.00) | RENMETAP2BCHE | |
| SCHEMBL14415351 | 1.00 | REN (1.00) | RENMETAP2BCHE | |
| SCHEMBL14415355 | 0.88 | REN (0.79) | RENMETAP2BCHE | |
| SCHEMBL7323798 | 0.88 | REN (0.79) | RENMETAP2BCHE | |
| SCHEMBL9858453 | 0.88 | REN (0.79) | RENMETAP2BCHE | |
| SCHEMBL7296545 | 0.88 | REN (0.79) | RENMETAP2BCHE | |
| SCHEMBL7284318 | 0.88 | REN (0.79) | RENMETAP2BCHE | |
| SCHEMBL9575598 | 0.88 | REN (0.79) | RENMETAP2BCHE | |
| SCHEMBL14415375 | 0.87 | REN (0.77) | RENMETAP2BCHE | |
| SCHEMBL14420373 | 0.87 | REN (0.77) | RENMETAP2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091425-A | Inhibitors of the catalytic action of renin | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |