Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857535 | 0.87 | CDK1 (0.40) | CDK1CCNB1CCNE1CDK2NT5E | |
| SCHEMBL9684215 | 0.87 | ADORA2A (0.40) | AHCYADORA2AADORA2B | |
| SCHEMBL9685345 | 0.87 | CDK1 (0.40) | CDK1CCNB1CCNE1CDK2NT5E | |
| SCHEMBL9685184 | 0.84 | PNP (0.47) | PNP | |
| SCHEMBL9417199 | 0.82 | CDK1 (0.39) | CDK1CCNB1CCNE1CDK2NT5E | |
| SCHEMBL9184996 | 0.82 | CDK1 (0.49) | CDK1CCNB1CCNE1CDK2NT5E | |
| SCHEMBL9684374 | 0.79 | CDK1 (0.43) | CDK1CCNB1CCNE1CDK2NT5E | |
| SCHEMBL9685521 | 0.78 | HSP90AA1 (0.35) | PNPHSP90AA1HSP90AB1 | |
| SCHEMBL9858021 | 0.77 | CDK1 (0.39) | CDK1CCNB1CCNE1CDK2NT5E | |
| SCHEMBL9684337 | 0.76 | HSP90AA1 (0.35) | CDK1CCNB1CCNE1CDK2NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |