Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632906 | 0.95 | KCNH3 (0.68) | KCNH3SMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL19392469 | 0.83 | HPGD (0.58) | KCNH3SMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL2392508 | 0.83 | KCNH3 (0.46) | KCNH3SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL22681015 | 0.80 | ALDH1A1 (0.51) | KCNH3SMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL10825975 | 0.78 | KCNH3 (0.50) | KCNH3SMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL175818 | 0.77 | NPC1 (0.56) | KCNH3SMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL25376808 | 0.77 | KMT2A (0.64) | ALDH1A1ATMPKM | |
| Hydrochloric Acid SCHEMBL10986438 | 0.77 | KCNH3 (0.52) | KCNH3SMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL22023245 | 0.76 | BACE1 (0.43) | KCNH3SMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL29204233 | 0.74 | EGLN2 (0.57) | KCNH3SMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162322-A | Anxiolytic agetns; humans, animals | A. H. ROBBINS COMPANY, INCORPORATED (US) | 1992-11-10 | — | — | US | disclosed |