Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684501 | 1.00 | EGFR (0.54) | EGFRHSD11B1HPGDKDM4EALDH1A1 | |
| SCHEMBL5040966 | 0.79 | CRHBP (0.67) | EGFRHPGDKDM4EALDH1A1CISD1 | |
| SCHEMBL5040968 | 0.79 | CRHBP (0.67) | EGFRHPGDKDM4EALDH1A1CISD1 | |
| SCHEMBL2871514 | 0.78 | DYRK1A (0.47) | HSD11B1HPGDALDH1A1POLBDYRK1A | |
| SCHEMBL338477 | 0.78 | DYRK1A (0.47) | HSD11B1HPGDALDH1A1POLBDYRK1A | |
| SCHEMBL4600830 | 0.74 | EGFR (0.85) | EGFRHPGDKDM4EALDH1A1CISD1 | |
| SCHEMBL4600832 | 0.74 | EGFR (0.85) | EGFRHPGDKDM4EALDH1A1CISD1 | |
| SCHEMBL10413058 | 0.74 | EGFR (0.85) | EGFRHPGDKDM4EALDH1A1CISD1 | |
| SCHEMBL7678076 | 0.73 | DYRK1A (0.53) | HSD11B1DYRK1ADYRK2DYRK1B | |
| SCHEMBL6046308 | 0.73 | EGFR (0.54) | EGFRHPGDKDM4EALDH1A1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134147-A | Antipsychotic agents | ADIR ET COMPAGNIE (FR) | 1992-07-28 | — | — | US | disclosed |
| US-5100902-A | Dopamine and Serotonin Antagonists, Antipsychotic Agents | ADIR ET COMPAGNIE (FR) | 1992-03-31 | — | — | US | disclosed |