Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.46 |
| ▸ | HTR2C | P28335 | 7/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325447 | 0.80 | HTR1A (0.49) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9685780 | 0.80 | HTR1A (0.50) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL1324801 | 0.80 | HTR1A (0.49) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9684200 | 0.79 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL8114295 | 0.79 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9684052 | 0.79 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL175879 | 0.79 | HTR1A (0.51) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL8786271 | 0.79 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9164783 | 0.78 | HTR1A (0.47) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL7332557 | 0.76 | HTR1A (0.51) | HTR1AHTR2CPDE3BPDE3ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |