Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.50 |
| ▸ | HTR2C | P28335 | 7/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175879 | 0.95 | HTR1A (0.51) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL9684901 | 0.90 | PDE3B (0.51) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL7762986 | 0.86 | HTR1A (0.45) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL6541577 | 0.84 | CMA1 (0.49) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL1325447 | 0.84 | HTR1A (0.49) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL1324801 | 0.84 | HTR1A (0.49) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL9204486 | 0.83 | MAPT (0.59) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL8114295 | 0.83 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL8786271 | 0.83 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3AMAPT | |
| SCHEMBL9684052 | 0.83 | HTR1A (0.48) | HTR1AHTR2CPDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |