Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 2/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | OGT | O15294 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217426 | 0.89 | CDC25B (0.54) | ALDH1A1CREBBPKDM4ECDC25BCDC25A | |
| SCHEMBL6647933 | 0.85 | ALDH1A1 (0.60) | ALDH1A1CREBBPKDM4ETDP1SMYD3 | |
| SCHEMBL29771053 | 0.82 | KDM4E (0.67) | ALDH1A1CREBBPKDM4ETDP1SMYD3 | |
| SCHEMBL118684 | 0.82 | KDM4E (0.67) | ALDH1A1CREBBPKDM4ETDP1SMYD3 | |
| SCHEMBL11788821 | 0.76 | CDC25B (0.64) | ALDH1A1KDM4ECDC25BCDC25AHSD17B10 | |
| SCHEMBL17260664 | 0.75 | KDM4E (0.62) | ALDH1A1CREBBPKDM4ETDP1SMYD3 | |
| SCHEMBL24897510 | 0.75 | CREBBP (0.58) | ALDH1A1CREBBPKDM4ESMYD3ESR1 | |
| SCHEMBL31191636 | 0.75 | CREBBP (0.58) | ALDH1A1CREBBPKDM4ESMYD3ESR1 | |
| SCHEMBL9684965 | 0.75 | ALDH1A1 (0.55) | ALDH1A1CREBBPKDM4ETDP1SMYD3 | |
| SCHEMBL6992123 | 0.74 | CREBBP (0.65) | ALDH1A1CREBBPKDM4ETDP1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |