Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | OGT | O15294 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647933 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL118684 | 0.76 | KDM4E (0.67) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL29771053 | 0.76 | KDM4E (0.67) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL17260664 | 0.75 | KDM4E (0.62) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL9684816 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL2546849 | 0.74 | CREBBP (0.69) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL349741 | 0.74 | CREBBP (0.65) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL6992123 | 0.74 | CREBBP (0.65) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL2316982 | 0.74 | KDM4E (0.69) | ALDH1A1KDM4ECREBBPPOLBTDP1 | |
| SCHEMBL9368243 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4ECREBBPPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |