Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065480 | 0.82 | HTR2A (0.50) | ALOX5TAAR1HTR2AHRH1 | |
| SCHEMBL28986139 | 0.78 | AOC3 (0.50) | AOC3TAAR1TRPA1MEN1KMT2A | |
| SCHEMBL3649127 | 0.77 | KMT2A (0.42) | AOC3ALOX5KMT2AHTR2AHRH1 | |
| Bicarbonate SCHEMBL6219599 | 0.75 | TRPA1 (0.55) | ALOX5TAAR1TRPA1MEN1KMT2A | |
| Acetone SCHEMBL28209188 | 0.74 | TRPA1 (0.53) | ALOX5TAAR1TRPA1MEN1KMT2A | |
| SCHEMBL28986115 | 0.73 | GAA (0.46) | AOC3 | |
| SCHEMBL4517622 | 0.73 | AOC3 (0.45) | AOC3TAAR1TRPA1KDM4EMEN1 | |
| SCHEMBL12143607 | 0.73 | AOC3 (0.69) | AOC3TAAR1TRPA1HTR2AHRH1 | |
| SCHEMBL12559942 | 0.73 | AOC3 (0.69) | AOC3TAAR1TRPA1HTR2AHRH1 | |
| SCHEMBL3430883 | 0.73 | AOC3 (0.69) | AOC3TAAR1TRPA1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513703-A2 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle | MAGIS FARMACEUTICI S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |