Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27990536 | 0.86 | CCR6 (0.66) | CCR6PAX8CNR2CETPALDH1A1 | |
| SCHEMBL17275425 | 0.85 | CCR6 (0.61) | CCR6PAX8CNR2CETPALDH1A1 | |
| SCHEMBL25628629 | 0.85 | CCR6 (0.64) | CCR6PAX8CNR2CETPALDH1A1 | |
| SCHEMBL9685806 | 0.84 | MAOA (0.46) | CCR6PAX8KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9684974 | 0.84 | MAOA (0.46) | CCR6PAX8KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL15508590 | 0.84 | CCR6 (0.63) | CCR6PAX8CNR2CETPALDH1A1 | |
| SCHEMBL10822625 | 0.83 | CCR6 (0.62) | CCR6PAX8CNR2CETPALDH1A1 | |
| SCHEMBL10823180 | 0.83 | CCR6 (0.62) | CCR6PAX8CNR2CETPALDH1A1 | |
| SCHEMBL10822929 | 0.83 | CCR6 (0.62) | CCR6PAX8CNR2CETPALDH1A1 | |
| SCHEMBL10822804 | 0.83 | CCR6 (0.62) | CCR6PAX8CNR2CETPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513703-A2 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle | MAGIS FARMACEUTICI S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |