Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685806 | 1.00 | MAOA (0.46) | MAOAMAOBKEAP1NFE2L2CCR6 | |
| SCHEMBL9684838 | 0.84 | CCR6 (0.52) | MAOAMAOBKEAP1NFE2L2CCR6 | |
| SCHEMBL990966 | 0.84 | ALDH1A1 (0.43) | MAOBALDH1A1MAPT | |
| SCHEMBL3170360 | 0.81 | CCR6 (0.52) | CCR6PAX8ALDH1A1BCHEACHE | |
| SCHEMBL8424282 | 0.81 | CCR6 (0.52) | CCR6PAX8ALDH1A1BCHEACHE | |
| SCHEMBL392019 | 0.80 | HTT (0.50) | CCR6PAX8ALDH1A1BCHEACHE | |
| SCHEMBL28002371 | 0.80 | HTT (0.50) | CCR6PAX8ALDH1A1BCHEACHE | |
| SCHEMBL30805121 | 0.80 | CCR6 (0.48) | CCR6PAX8ALDH1A1BCHEACHE | |
| SCHEMBL27267384 | 0.80 | CCR6 (0.48) | CCR6PAX8ALDH1A1BCHEACHE | |
| SCHEMBL19346032 | 0.80 | CCR6 (0.53) | CCR6PAX8ALDH1A1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513703-A2 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle | MAGIS FARMACEUTICI S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |