Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699751 | 0.92 | CSNK2A2 (0.48) | MPOCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL6954586 | 0.83 | ATM (0.43) | MPOMEN1KMT2AMAPT | |
| SCHEMBL8118256 | 0.81 | PTGIR (0.48) | MPOCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL366356 | 0.80 | MAPT (0.46) | MAPTTDP1CXCR4 | |
| SCHEMBL17223973 | 0.80 | CXCR4 (0.38) | MPOMAPTCXCR4 | |
| SCHEMBL17528648 | 0.80 | TLR8 (0.54) | MPOMEN1KMT2AMAPTTDP1 | |
| SCHEMBL14799694 | 0.80 | TLR8 (0.54) | MPOMEN1KMT2AMAPTTDP1 | |
| SCHEMBL19138003 | 0.80 | SLC9A1 (0.43) | MAPTTDP1CXCR4SMN1; SMN2 | |
| SCHEMBL11325500 | 0.80 | TLR8 (0.54) | MPOMEN1KMT2AMAPTTDP1 | |
| SCHEMBL892083 | 0.80 | TLR8 (0.54) | MPOMEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5097041-A | PURIFICATION OF 2-ARYL-2H-BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0424316-A2 | Purification of 2-aryl-2h-benzotriazoles | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |