SCHEMBL9685024

SCHEMBL9685024

Cc1cc(C)c(CO)cc1CO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.50
PGK1 P00558 1/20 0.48
PGK2 P07205 1/20 0.48
NPSR1 Q6W5P4 2/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
PKM P14618 1/20 0.37
HSD17B10 Q99714 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
KDM4E B2RXH2 2/20 0.36
CASP6 P55212 1/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.33
PDCD1 Q15116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394846 0.91 SHBG (0.48) SHBGPGK1PGK2NPSR1PDE4A
SCHEMBL5097086 0.90 SHBG (0.52) SHBGPGK1PGK2NPSR1PDE4A
SCHEMBL5075167 0.84 SHBG (0.54) SHBGPGK1PGK2NPSR1PKM
SCHEMBL28472333 0.84 SHBG (0.48) SHBGPGK1PGK2NPSR1PKM
SCHEMBL9731686 0.83 ALDH1A1 (0.39) SHBGPGK1PGK2NPSR1PDE4A
SCHEMBL12372943 0.83 SHBG (0.39) SHBGPGK1PGK2HSD17B10CYP2D6
SCHEMBL21413071 0.82 SHBG (0.42) SHBGPGK1PGK2NPSR1PDE4A
SCHEMBL22817443 0.82 SHBG (0.42) SHBGPGK1PGK2NPSR1PDE4A
SCHEMBL14924927 0.82 SHBG (0.42) SHBGPGK1PGK2NPSR1PDE4A
SCHEMBL14386683 0.82 ALDH1A1 (0.54) SHBGPGK1PGK2PKMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105418868-A Boron modified phenolic resin, preparation method and friction material SHANDONG SHENGQUAN NEW MAT CO LTD 2016-03-23 CN claimed
CN-105418868-B Boron modified phenolic resin, preparation method and friction material 山东圣泉新材料股份有限公司 2017-07-25 CN disclosed
CN-105418868-A Boron modified phenolic resin, preparation method and friction material SHANDONG SHENGQUAN NEW MAT CO LTD 2016-03-23 CN disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
WO-2010095678-A1 FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM セントラル硝子株式会社 (JP) 2010-08-26 WO disclosed
US-5138090-A Administering to inhibit HMG-CoA reductase BAYER AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
US-5122442-A Water soluble binder; photosensitive compound HOECHST CELANESE CORPORATION (US) 1992-06-16 US disclosed
EP-0388732-A2 Pentasubstituted phenyls BAYER AG (DE) 1990-09-26 EP disclosed
EP-0212482-B1 PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS HOECHST CELANESE CORPORATION (US) 1989-04-19 EP disclosed
EP-0212482-A2 Process for obtaining negative images from positive photoresists HOECHST CELANESE CORPORATION (US) 1987-03-04 EP disclosed
EP-0200777-A1 NEW AMINO COMPOUNDS, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1986-11-12 EP disclosed
EP-0061150-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME AMERICAN HOECHST CORPORATION (US) 1986-10-15 EP disclosed
WO-1986002645-A1 NEW AMINO COMPOUNDS, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT M (DE) 1986-05-09 WO disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed
EP-0061150-A1 Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same AMERICAN HOECHST CORPORATION (US) 1982-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 SHBG 4861/4885PGK1 3551/4885PGK2 2718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.