SCHEMBL9685057

SCHEMBL9685057

CC(=O)OC(OC(C)=O)c1c(C)c(C)cc(C)c1C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
CYP3A4 P08684 2/20 0.32
ABCB1 P08183 1/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACHE P22303 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26507122 0.73 MAPT (0.35) TSHRCYP3A4KDM4EALDH1A1TDP1
SCHEMBL7948115 0.72 ALDH1A1 (0.37) TSHRCYP3A4KDM4EALDH1A1TDP1
SCHEMBL20679770 0.71 KDM4E (0.33) CYP3A4KDM4EACHE
SCHEMBL20879477 0.68 TDP1 (0.41) TSHRCYP3A4ABCB1POLBALDH1A1
SCHEMBL10938410 0.67 POLB (0.49) KDM4EPOLBALDH1A1TDP1ACHE
SCHEMBL17863579 0.66 ALDH1A1 (0.48) TSHRCYP3A4ALDH1A1ACHE
SCHEMBL12703564 0.65 ESR1 (0.47) CYP3A4KDM4EALDH1A1
SCHEMBL28758397 0.65 TSHR (0.39) TSHRCYP3A4KDM4EALDH1A1ACHE
Ammonia Solution, Strong SCHEMBL28214056 0.65 POLB (0.47) KDM4EPOLBALDH1A1TDP1ACHE
SCHEMBL7949922 0.65 KDM4E (0.40) TSHRKDM4EPOLBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5122442-A Water soluble binder; photosensitive compound HOECHST CELANESE CORPORATION (US) 1992-06-16 US disclosed
EP-0212482-B1 PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS HOECHST CELANESE CORPORATION (US) 1989-04-19 EP disclosed
EP-0212482-A2 Process for obtaining negative images from positive photoresists HOECHST CELANESE CORPORATION (US) 1987-03-04 EP disclosed
EP-0061150-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME AMERICAN HOECHST CORPORATION (US) 1986-10-15 EP disclosed
EP-0061150-A1 Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same AMERICAN HOECHST CORPORATION (US) 1982-09-29 EP disclosed