Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348272 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL10348274 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL10348273 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL9661045 | 0.82 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19MAPTMEN1 | |
| SCHEMBL9200696 | 0.80 | KCNH2 (0.40) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL9684999 | 0.80 | KCNH2 (0.48) | CYP1A2MAPTMEN1KMT2APOLB | |
| SCHEMBL10892820 | 0.80 | KCNH2 (0.48) | CYP1A2MAPTMEN1KMT2APOLB | |
| SCHEMBL10892807 | 0.80 | KCNH2 (0.48) | CYP1A2MAPTMEN1KMT2APOLB | |
| SCHEMBL11613063 | 0.79 | ABCC9 (0.42) | MAPTMEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL11613059 | 0.79 | ABCC9 (0.42) | MAPTMEN1KMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164509-A | BENZODIAZOLO ANALOGS | E. R. SQUIBB & SONS, INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0488107-A2 | Tricyclic benzodiazole analogs and their use in the treatment of cardiovascular disorders | E.R. SQUIBB & SONS, INC. (US) | 1992-06-03 | — | — | EP | disclosed |