Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | ADCY5 | O95622 | 11/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 3/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685206 | 0.88 | FDPS (0.43) | ADORA2AADCY5 | |
| SCHEMBL9686031 | 0.84 | ADORA3 (0.47) | ADORA2AADORA3ADORA1 | |
| SCHEMBL6045681 | 0.78 | ADCY5 (0.62) | ADORA2AADCY5CYP1A2CYP3A4NFKB1 | |
| SCHEMBL6045512 | 0.78 | ADCY5 (0.62) | ADORA2AADCY5CYP1A2CYP3A4NFKB1 | |
| SCHEMBL6045801 | 0.78 | ADCY5 (0.62) | ADORA2AADCY5CYP1A2CYP3A4NFKB1 | |
| SCHEMBL6045575 | 0.78 | ADCY5 (0.62) | ADORA2AADCY5CYP1A2CYP3A4NFKB1 | |
| SCHEMBL9684255 | 0.77 | ADCY5 (0.72) | ADORA2AADCY5PI4KAPI4K2BPI4K2A | |
| SCHEMBL17157383 | 0.76 | ADCY5 (0.64) | ADORA2AADCY5CYP1A2CYP3A4NFKB1 | |
| SCHEMBL15743402 | 0.76 | ADCY5 (0.64) | ADORA2AADCY5CYP1A2CYP3A4NFKB1 | |
| SCHEMBL17157337 | 0.76 | ADCY5 (0.64) | ADORA2AADCY5CYP1A2CYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468866-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | claimed |
| EP-0468866-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468119-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |