Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | POLG | P54098 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683747 | 0.97 | ADORA2A (0.43) | CYP3A4CYP2D6FGFR1ADORA2AADORA1 | |
| SCHEMBL9858339 | 0.87 | FGFR1 (0.50) | CYP3A4CYP2D6FGFR1ADORA2AADORA1 | |
| SCHEMBL9683394 | 0.86 | FDPS (0.41) | CYP3A4CYP2D6FGFR1 | |
| SCHEMBL9684374 | 0.85 | CDK1 (0.43) | CYP3A4CYP2D6FGFR1NT5E | |
| SCHEMBL9417160 | 0.84 | SLC22A6 (0.50) | CYP3A4CYP2D6FGFR1ADORA2AADORA1 | |
| SCHEMBL9684116 | 0.83 | FGFR1 (0.52) | CYP3A4CYP2D6FGFR1ADORA2AADORA1 | |
| SCHEMBL9683381 | 0.83 | FDPS (0.42) | FGFR1 | |
| SCHEMBL9674904 | 0.82 | ADORA2A (0.40) | CYP3A4CYP2D6FGFR1ADORA2AADORA1 | |
| SCHEMBL9683794 | 0.81 | CYP3A4 (0.41) | CYP3A4CYP2D6FGFR1ADORA2AADORA1 | |
| SCHEMBL9127128 | 0.81 | FAP (0.48) | CYP3A4CYP2D6FGFR1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | claimed |
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |
| EP-0396082-A2 | New carnitine derivatives, process for their preparation, and their use in human therapy | FIDIA S.p.A. (IT) | 1990-11-07 | — | — | EP | disclosed |