Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685772 | 0.90 | AGTR1 (0.56) | AGTR1MEN1KMT2AAGTR2 | |
| SCHEMBL9685819 | 0.89 | AGTR1 (0.57) | AGTR1MEN1KMT2AAGTR2 | |
| SCHEMBL9685773 | 0.83 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9685865 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9163668 | 0.75 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9422648 | 0.75 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9165250 | 0.74 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL9685271 | 0.72 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9434830 | 0.71 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL11404329 | 0.71 | MEN1 (0.63) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485929-A1 | Substituted azoles, process for their preparation and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-20 | — | — | EP | disclosed |