Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.66 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.66 |
| ▸ | PPARG | P37231 | 8/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192299 | 0.80 | AGTR1 (1.00) | AGTR1AGTR2PPARGPOLB | |
| SCHEMBL9118635 | 0.78 | PPARG (0.69) | AGTR1AGTR2PPARG | |
| SCHEMBL9119861 | 0.76 | AGTR1 (0.64) | AGTR1AGTR2PPARGPOLBLMNA | |
| SCHEMBL9089333 | 0.75 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL9201172 | 0.75 | DRD2 (0.78) | AGTR1AGTR2PPARGPOLBMAPT | |
| SCHEMBL8396958 | 0.74 | PPARG (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9123025 | 0.73 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9120627 | 0.73 | PPARG (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL9685819 | 0.73 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9041506 | 0.72 | PPARG (0.73) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011365-A1 | SUBSTITUTED BENZIMIDAZOLES AND QUINAZOLINES AS ANTIHYPERTENSIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-05-26 | — | — | WO | claimed |