Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685863 | 0.80 | MAPT (0.36) | MAPTALDH1A1THRBLCKGLA | |
| SCHEMBL9685859 | 0.80 | MAPT (0.36) | MAPTALDH1A1THRBLCKGLA | |
| SCHEMBL9685509 | 0.76 | PTPRC (0.50) | MAPTALDH1A1THRBLCKGLA | |
| SCHEMBL9684529 | 0.75 | ALDH1A1 (0.40) | MAPTALDH1A1THRBMEN1KMT2A | |
| SCHEMBL9685886 | 0.75 | CDC25B (0.42) | MAPTALDH1A1THRBMEN1KMT2A | |
| SCHEMBL9423239 | 0.75 | MAPT (0.38) | MAPTALDH1A1THRBMEN1KMT2A | |
| SCHEMBL9684787 | 0.75 | SOAT1 (0.39) | MAPTALDH1A1THRBMEN1KMT2A | |
| SCHEMBL9683960 | 0.73 | GRK6 (0.49) | MAPTALDH1A1THRBGLAMEN1 | |
| SCHEMBL5158317 | 0.72 | MAPT (0.48) | MAPTALDH1A1THRBGLAMEN1 | |
| SCHEMBL7462537 | 0.71 | PTPRC (0.55) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |