Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474803 | 1.00 | PARP10 (0.46) | PARP10HSD17B10PARP1PARP4CA1 | |
| Hydrochloric Acid SCHEMBL11466948 | 0.98 | PARP10 (0.44) | PARP10HSD17B10PARP1PARP4CA1 | |
| SCHEMBL1250863 | 0.81 | ALDH1A1 (0.50) | PARP10HSD17B10PARP1PARP4CA1 | |
| SCHEMBL5616922 | 0.81 | PARP10 (0.48) | PARP10HSD17B10PARP1PARP4CA1 | |
| SCHEMBL11466438 | 0.81 | PLK1 (0.47) | CA2TSHR | |
| SCHEMBL27642087 | 0.81 | HSD17B10 (0.44) | PARP10HSD17B10PARP1PARP4CA1 | |
| SCHEMBL20504349 | 0.81 | LOXL2 (0.54) | CA1CA2ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL19464655 | 0.81 | HSD17B10 (0.48) | PARP10HSD17B10PARP1PARP4CA1 | |
| SCHEMBL14236756 | 0.79 | PARP10 (0.47) | PARP10HSD17B10PARP1PARP4CA1 | |
| SCHEMBL6370728 | 0.78 | PARP10 (0.46) | PARP10HSD17B10PARP1PARP4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |