Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783529 | 0.85 | L3MBTL1 (0.84) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL2345631 | 0.84 | L3MBTL1 (0.61) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL9262266 | 0.83 | CYP1A2 (0.51) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL5657713 | 0.82 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL9270489 | 0.81 | L3MBTL1 (0.43) | L3MBTL1MAPTNPSR1HPGDKDM4E | |
| SCHEMBL6274367 | 0.81 | TDP1 (0.48) | L3MBTL1MAPTNPSR1HPGDKDM4E | |
| SCHEMBL6275145 | 0.81 | LMNA (0.53) | L3MBTL1MAPTNPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL15923458 | 0.80 | LMNA (0.51) | L3MBTL1MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL4860922 | 0.80 | L3MBTL1 (0.56) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL7215472 | 0.80 | MAPT (0.44) | L3MBTL1MAPTNPSR1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |